Linear 1 3-diarylpropanoids
Medchemexpress LLC 1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one | 149732-52-5 | 292.33 | 5 MG
1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one is a potent nucleocapsid (N) protein inhibitor isolated from *Curcuma kwangsiensis*. It demonstrates excellent antiviral activity against HCoV-OC43 and SARS-CoV-2.
- Inhibits nucleocapsid (N) protein
- Exhibits antiviral activity against HCoV-OC43 and SARS-CoV-2
- Active against various cell lines (KB, PC-12, Vero)
Medchemexpress LLC Avobenzone | 70356-09-1 | 98.0% | 5 G
Avobenzone, a dibenzoylmethane compound, is one of the most widely used filters in sunscreens for skin photoprotection in the UVA band. It is also an endocrine disruptor that directly binds to estrogen receptor β and acts as an estrogen agonist.
- Promotes adipogenesis in hBM-MSCs
- Up-regulates mRNA levels of PPARγ during adipogenesis
- Inhibits proliferative activities of human trophoblast cells
- Induces apoptosis in HTR8/SVneo cells
- Shows weak ERα agonism and weak AR antagonism
Apexbio Technology LLC Avobenzone 70356-09-1 200mg
Avobenzone (70356-09-1) is a small-molecule agonist targeting estrogen receptor (ER ) It is designed to bind directly to ER thereby modulating endocrine signaling pathways Avobenzone exerts its biological activity primarily through direct receptor binding and estrogenic agonist activity Based on these properties Avobenzone holds research potential in studies investigating endocrine-disrupting chemicals mechanisms of photoprotection UV-induced cellular damage and skin pathology
Medchemexpress LLC (R)-(-)-1,2-propanediol | 4254-14-2 | MFCD00066248 | 25g
(R)-(-)-1 2-Propanediol is a (R)-enantiomer of 1 2-Propanediol that produced from glucose in Escherichia coli expressing NADH-linked glycerol dehydrogenase genes[1]
Medchemexpress LLC (R)-(-)-1,2-propanediol | 4254-14-2 | MFCD00066248 | 100g
(R)-(-)-1 2-Propanediol is a (R)-enantiomer of 1 2-Propanediol that produced from glucose in Escherichia coli expressing NADH-linked glycerol dehydrogenase genes[1]
Medchemexpress LLC Dibenzoylmethane | 120-46-7 | 98.0% | 224.26 | 100 G
Dibenzoylmethane is a minor ingredient found in licorice that activates Nrf2. It helps prevent various cancers and oxidative damage. As an analog of curcumin, it causes the dissociation from Keap1 and nuclear translocation of Nrf2.
- Activates Nrf2
- Helps prevent various cancers
- Helps prevent oxidative damage
- Analog of curcumin
- Causes dissociation from Keap1 and nuclear translocation of Nrf2
Medchemexpress LLC Dibenzoylmethane | 120-46-7 | MFCD00003085 | 98.0% | 224.26 | 5 G
Dibenzoylmethane, a minor ingredient in licorice, activates Nrf2 and prevents various cancers and oxidative damage. It is an analog of curcumin that causes dissociation from Keap1 and nuclear translocation of Nrf2. This product is for research use only and not intended for sale to patients.
- Activates Nrf2
- Prevents various cancers and oxidative damage
- Analog of curcumin
- Causes dissociation from Keap1 and nuclear translocation of Nrf2
Medchemexpress LLC (R)-(-)-1,2-propanediol | 4254-14-2 | MFCD00066248 | 10g
(R)-(-)-1 2-Propanediol is a (R)-enantiomer of 1 2-Propanediol that produced from glucose in Escherichia coli expressing NADH-linked glycerol dehydrogenase genes[1]
Medchemexpress LLC Avobenzone | 70356-09-1 | 98.0% | 10 MM 1 ML
Avobenzone is a dibenzoylmethane compound that is widely used as a filter in sunscreens for skin photoprotection in the UVA band. It is also identified as an endocrine disruptor that directly binds to estrogen receptor β and functions as an estrogen agonist.
- Long-Wave UVA Filter.
- Significantly promotes adipogenesis in hBM-MSCs at an EC50 of 14.1 μM.
- Up-regulates mRNA levels of PPARγ during adipogenesis in hBM-MSCs at 10 μM.
- Inhibits proliferative activities of human trophoblast cells and induces apoptosis in HTR8/SVneo cells at concentrations of 1-50 μM over 48 hours.
- Exhibits weak ERα agonism and weak AR antagonism.
TARGETMOL CHEMICALS INC ISOBAVACHALCONE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Isobavachalcone (Corylifolinin) is a chalcone constituent of Angelica keiskei has potent anti-inflammatory activity possible can ameliorate neuronal injury in brain diseases associated with inflammation. purity: 99%
Medchemexpress LLC Phlorizin | 60-81-1 | 99.9% | 436.41 | 5 G
Phlorizin is a non-selective SGLT inhibitor that acts on hSGLT1 and hSGLT2. It also functions as a Na+/K+-ATPase inhibitor.
- Non-selective SGLT inhibitor.
- Inhibits hSGLT1 and hSGLT2.
- Na+/K+-ATPase inhibitor.
- Decreases blood glucose levels.
- Prevents nerve fiber decrease and retinal abnormalities.
Selleck Chemical LLC Phlorizin S2343-1g
Phlorizin (Phloridzin) is a dihydrochalcone found in the bark of pear (Pyrus communis) apple cherry and other fruit trees Phlorizin is a non-selective SGLT inhibitor with Ki of 300 nM and 39 nM for hSGLT1 and hSGLT2 respectively Phlorizin is also a Na /K -ATPase inhibitor
Selleck Chemical LLC Phloretin (RJC 02792) S2342-10mM/1mL
Phloretin (RJC 02792 NSC 407292 Dihydronaringenin) is a dihydrochalcone found in apple tree leaves which shows beneficial effects on diabetes